RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-652
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
Echocardiography; PCR etc.
Target
JAGGED-1
Pathway
NA
PubMed ID
Title
Therapeutic silencing of miR-652 restores heart function and attenuates adverse remodeling in a setting of established pathological hypertrophy
Year
2014
Function
Jagged1 (a notch1 ligand) as a novel direct target of miR-652.miR-652 protects the heart against pathological remodeling and improves heart function.